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​Award-Winning
"Best Exosome Serum 2024," New Beauty®
Times Magazine Best Invention 2024
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The Most Advanced Anti-Aging Solution: INTENSE Serum
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1 Trillion+ exosomes in every bottle for clinically proven results within 6 weeks
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Improves the appearance of fine lines and wrinkles
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Improves luminosity for a radiant glow
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Rapidly reduces the appearance of redness and brown spots​

“If you cut yourself, what's the first responder?” says Rion Aesthetics CEO Alisa Lask. “Platelets—your blood.” Going off that premise, creators of Rion’s Plated Intense Serum purchase platelets from a blood bank to harness the type of exosome—an inter-cellular messenger—responsible for signaling cell renewal. With billions of exosomes per two-pump dose, Plated uses its Renewosome technology to decrease facial redness and maintain shelf stability of the serum—a challenge for stem cell-containing products. The company has the medical credentials: Rion was founded by Mayo Clinic physicians at the Van Cleve Cardiac Regenerative Medicine Program, where they discovered that exosomes play a key role in healing. The company now produces platelet-derived exosome products currently in clinical trials for wound healing, cardiology, and orthopedics, while Lask’s spinoff focuses on aesthetic applications. A 2023 clinical study found that “all patients experienced improvement in redness, skin irritation, skin tone, texture, and smoothness” with nine weeks of Plated use.


